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Area of active basic science, translational, and clinical research include:

  • Antimicrobial Stewardship: Utility of Provider Reports, Best Practice Alerts
  • Basic Science: Antibiotic Synergy for Multi-Drug Resistant Organisms
  • Global Health: Diarrheal Diseases in Jamaica, Multidrug Resistant Organisms in Bangladesh
  • Diagnostics: T2Bacteria Panel
  • Solid Organ Transplantation: HOPE in Action, Fungal Infections, Antibiotic Stewardship, Diagnostic Stewardship

Active Clinical Trials

HOPE in Action Prospective Multicenter, Clinical Trial of HIV+ Deceased Donor Liver Transplant for HIV+ Recipients
Site PI: Jonathan Hand, MD

Kidney Transplantation in Recipients and Donors with HIV: Long Term Follow Up Study
Site PI: Jonathan Hand, MD

A Study of Vaccination with 9-valent Extraintestinal Pathogenic Escherichia Coli Vaccine (ExPEC9V) in the Prevention of Invasive Extraintestinal Pathogenic Escherichia Coli Disease in Adults Aged 60-Years and Older with a History of Urinary Tract Infection in the Past 2 Years
Site PI: Jonathan Hand, MD

A randomized study to evaluate antibody response to an additional dose of SARS-CoV-2 vaccination with and without immunosuppression reduction in kidney and liver transplant recipients
Site PI: Jonathan Hand, MD

A Phase 4 Study Using a Test-Negative Design to Evaluate the Effectiveness of a 20-valent Pneumococcal Conjugate Vaccine against Vaccine-Type Radiologically-Confirmed Community-Acquired Pneumonia in Adults ≥65 Years of Age
Site PI: Jonathan Hand, MD

A Phase-3, Multicenter, Prospective, Randomized, Double-Blind Study of Two Treatment Regimens for Candidemia and/or Invasive Candidiasis: Intravenous Echinocandin followed by Oral Ibrexafungerp versus Intravenous Echinocandin followed by Oral Fluconazole
Site PI: Jonathan Hand, MD